Regional data on climate, river runoff and inventory of glaciers within High Mountainous Asia were used as informational basis to elaborate new approach in computing components of the hydrological cycle (glaciers runoff, evaporation, precipitation). In order to improve and optimize the calculation methodology, 4 675 homogeneous groups of glaciers were identified in the largest Asian river basins, i.e., Amu Darya, Syr Darya, Indus, Ganges, Brahmaputra, Tarim, and others. As the classification criteria for 53 225 glaciers located there, the author consistently used 8 gradations of orientation (azimuth) and 23 gradations of area. Calculating of the hydrological regime of glaciers was performed on the example of several Asian river basins. It has been shown that in the drainless basins in Asia, the only potential factor of the glacial influence on the changes in global Ocean level is the seasonal amount of evaporation from the melted surface of perennial ice and old firn. These results and published sources were used for re-evaluation of the previous conclusions on the influence of glacier runoff on change of the Ocean level. Comparison of measured and calculated annual river runoff, which was obtained by means of modeling the components of water-balance equation, showed good correspondence between these variables.